GBE422 Industrial Genetics and Bioengineering IIIstanbul Okan UniversityDegree Programs Genetics and Bioengineering (English)General Information For StudentsDiploma SupplementErasmus Policy StatementNational Qualifications
Genetics and Bioengineering (English)
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

General course introduction information

Course Code: GBE422
Course Name: Industrial Genetics and Bioengineering II
Course Semester: Fall
Course Credits:
Theoretical Practical Credit ECTS
4 4 6 11
Language of instruction: EN
Course Requisites:
Does the Course Require Work Experience?: No
Type of course: Compulsory
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Dr.Öğr.Üyesi ELİF KUBAT ÖKTEM
Course Lecturer(s):
Course Assistants:

Course Objective and Content

Course Objectives: At the end of this course the student will also be able to:
• define the structure and function of plant cell and organelles,
• develop fundamental knowledge in plant tissue culture and plant biotechnology,
• explain the techniques used for plant transformation,
• describe methodologies in transgenic plants and genetically modified organisms,
• provide knowledge in intellectual property rights in plant biotechnology
• familiar with basic bioinformatic tools used in plant science,
Course Content: • History of biotechnological processes
• Microbial Enzymes
• Pre-fermentation processes
• Post-fermentation processes
• Industrial chemicals and fuels
• Industrial microorganisms
• Culture collection
• Lecture and discussion
• Lecture and discussion
• catabolism
• Glycolytic track paths
• Glycolysis
• Anaerobic respiration
• Anabolizma
• Kinetic velocity equations
• Care energy and endogenesis respiration
• Product formation kinetic modeling
• Kinetic models of substrate use
• Anaerobic reproduction without external electron donors
• Reproduction stoichiometry
• Semi-reaction concept
• Dying coefficient
• Maintenance coefficient
• Specific breeding rate
• Efficiency in aerobic reproduction
• Anaerobic product formation
• Discrete systems advantages and disadvantages
• Advantages and disadvantages of semi-batch systems
• Continuous systems advantages and disadvantages
• Measurement of kinetic parameters in discrete system
• Oxygen restriction in discrete system
• Monod model and maintenance mechanism in continuous systems
• Yoghurt and buttermilk production
• Production of kefir and red
• Cheese and butter technology
• Sausage production
• Pickle production
• Vinegar production
• Bread technology
• Sourdough technology
• Turnip production
• Boza production
• Tarhana production
• Nutraceutical foods
• pharmafoods
• Fitösötik on
• Probiotic, prebiotic and symbiotics
• The benefits of probiotic bacteria
• Single cell protein characterization
• Industrial microbial enzymes
• Deep culture technique
• Alkaline method in cell disruption
• Osmotic shock, ultra sound, lysozyme applications in cell disruption
• Antibiotics
• Organic acids
• Vitamins
• Amino acids
• Organic acids
• Diacetyl
• Carbon dioxide
•Hydrogen peroxide
• bacteriocins

Learning Outcomes

The students who have succeeded in this course;
Learning Outcomes
1 - Knowledge
Theoretical - Conceptual
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
1) At the end of this course, students will learn the application areas and properties of bioprocess technologies.
Competence to Work Independently and Take Responsibility

Lesson Plan

Week Subject Related Preparation
1) • History of biotechnological processes • Microbial Enzymes • Pre-fermentation processes • Post-fermentation processes • Industrial chemicals and fuels • Plant Biotechnology History and Its Importance -
2) • Industrial microorganisms • Culture collection • Mutagenesis-recombinant DNA • Improvement of fermentation microorganisms • Culture protection -
3) • catabolism • Glycolytic track paths • Glycolysis • Anaerobic respiration • Anabolizma • Plant tissue culture techniques -
4) • Kinetic velocity equations • Care energy and endogenesis respiration • Product formation kinetic modeling • Kinetic models of substrate use • Anaerobic reproduction without external electron donors • Techniques for Plant Transformation -
5) • Reproduction stoichiometry • Semi-reaction concept • Dying coefficient • Maintenance coefficient • Specific breeding rate • Efficiency in aerobic reproduction • Anaerobic product formation • Transgenic plants for crop improvement • Genetically modified organisms -
6) • Discrete systems advantages and disadvantages • Advantages and disadvantages of semi-batch systems • Continuous systems advantages and disadvantages • Measurement of kinetic parameters in discrete system • Oxygen restriction in discrete system • Monod model and maintenance mechanism in continuous systems • Field / Laboratory work -
7) • MIDTERM -
8) • Yoghurt and buttermilk production • Production of kefir and red • Cheese and butter technology • Sausage production • Intellectual property rights in plant biotechnology -
9) • Turşu üretimi • Sirke üretimi • Ekmek teknolojisi • Ekşi hamur teknolojisi -
10) • Turnip production • Boza production • Tarhana production -
11) • Nutraceutical foods • pharmafoods • Fitösötik on • Probiotic, prebiotic and symbiotics • The benefits of probiotic bacteria -
12) • Single cell protein characterization • Industrial microbial enzymes • Deep culture technique • Alkaline method in cell disruption • Osmotic shock, ultra sound, lysozyme applications in cell disruption -
13) • Antibiotics • Organic acids • Vitamins • Amino acids -
14) • Organic acids • Diacetyl • Carbon dioxide •Hydrogen peroxide • bacteriocins -
15) final exam -

Sources

Course Notes / Textbooks: • Biyoreaksiyon Mühendisliği, Biyolojik Proseslerin Kinetiği ve Modellenmesi, Su Vakfı Yayınları, Kocaeli, 2005
• Plant Biotechnology: The Genetic Manipulation of Plants (2nd ed.) by Adrian Slater, Nigel W. Scott, and Mark R. Fowler, 2012.
• Introduction to Biotechnology (2nd ed.) by Thieman, W. J. and Palladino M. A., 2009.
• Plants from Test Tubes by L. Kyte and J. Kleyn, 1996.
• Micropropagation by P. Debergh and R. H. Zimmerman, 1994
References: • Biyoreaksiyon Mühendisliği, Biyolojik Proseslerin Kinetiği ve Modellenmesi, Su Vakfı Yayınları, Kocaeli, 2005
• Plant Biotechnology: The Genetic Manipulation of Plants (2nd ed.) by Adrian Slater, Nigel W. Scott, and Mark R. Fowler, 2012.
• Introduction to Biotechnology (2nd ed.) by Thieman, W. J. and Palladino M. A., 2009.
• Plants from Test Tubes by L. Kyte and J. Kleyn, 1996.
• Micropropagation by P. Debergh and R. H. Zimmerman, 1994

Course-Program Learning Outcome Relationship

Learning Outcomes

1

Program Outcomes
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose. 1
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.) 1
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively. 1
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill. 1
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions. 1
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal. 1
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development. 1
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions. 1

Learning Activity and Teaching Methods

Expression
Brainstorming/ Six tihnking hats
Lesson
Project preparation

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Application
Group project
Presentation
Reporting

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Attendance 15 % 10
Presentation 1 % 15
Project 1 % 20
Midterms 1 % 25
Final 1 % 30
total % 100
PERCENTAGE OF SEMESTER WORK % 70
PERCENTAGE OF FINAL WORK % 30
total % 100

Workload and ECTS Credit Grading

Activities Number of Activities Duration (Hours) Workload
Course Hours 15 4 60
Laboratory 15 4 60
Presentations / Seminar 1 2 2
Midterms 1 2 2
Final 1 2 2
Total Workload 126