GBE203 BiochemistryIstanbul Okan UniversityDegree Programs Genetics and Bioengineering (English)General Information For StudentsDiploma SupplementErasmus Policy StatementNational Qualifications
Genetics and Bioengineering (English)
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

General course introduction information

Course Code: GBE203
Course Name: Biochemistry
Course Semester: Fall
Course Credits:
Theoretical Practical Credit ECTS
2 2 3 5
Language of instruction: EN
Course Requisites:
Does the Course Require Work Experience?: No
Type of course: Compulsory
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Dr.Öğr.Üyesi SEVDA MERT
Course Lecturer(s): Dr.Öğr.Üyesi SEVDA MERT
Course Assistants:

Course Objective and Content

Course Objectives: The aim of this course is to train students to understand biological processes and events by learning the logic of biochemistry.
Course Content: Describe general cell structure and subcellular organelles, describe the structure and metabolic function of carbohydrates, lipids, proteins and nucleic acids, describe the functions, properties and mechanisms of enzymes, describe the biochemical function of vitamines, describe the biochemical function of membrane, describe the metabolism in cytoplasm, mitochondria and nucleus, summerize the metabolism of amino acid and proteins, carbohydrates and lipids in different compartments of the cell, describe metabolic disorders of amino acid and proteins, carbohydrates and lipids, understand the principles of laboratory tests.

Learning Outcomes

The students who have succeeded in this course;
Learning Outcomes
1 - Knowledge
Theoretical - Conceptual
1) The student will be able to describe general cell structure and subcellular organelles
2 - Skills
Cognitive - Practical
1) The student will be able to understand the principles of laboratory tests.
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
1) The student will be able to describe the structure and metabolic function of carbohydrates, lipids, proteins and nucleic acids.
2) The student will be able to describe the functions, properties and mechanisms of enzymes
3) The student will be able to describe the biochemical function of vitamins
4) The student will be able to describe the biochemical function of membrane
5) The student will be able to describe the metabolism in cytoplasm, mitochondria and nucleus
6) The student will be able to summarize the metabolism of amino acid and proteins, carbohydrates and lipids in different compartments of the cell.
7) The student will be able to describe metabolic disorders of amino acid and proteins, carbohydrates and lipids.
Competence to Work Independently and Take Responsibility

Lesson Plan

Week Subject Related Preparation
1) • General cell structure and subcellular organelles • Laboratory safety • Clinical laboratories supplies Lecture notes and powerpoint presentation
2) • The components of the cell: Carbohydrates • General reaction of amino acids and proteins • Plasma protein electrophoresis Lecture notes and powerpoint presentation
3) • The components of the cell: Lipids • General reactions of carbohydrates • Specimen of blood Lecture notes and powerpoint presentation
4) • The components of the cell: Proteins •Ultracentrifugation, SDS-gel electrophoresis, gel filtration chromatography techniques • General reaction of lipids • Lipoprotein electrophoresis Lecture notes and powerpoint presentation
5) • The components of the cell: Nucleic acids .PCR, agarose gel electrophoresis, Northern and Southern blot techiques • Electrolytes • pH and buffer systems • Types of solutions • The concept of pH Lecture notes and powerpoint presentation
6) • Enzymes .PYMOL • Basic separation techniques • Assesment of hemoglobin and bilirubin Lecture notes and powerpoint presentation
7) • Water and electrolytes • Spectroscopic analysis methods Lecture notes and powerpoint presentation
8) Midterm Exam I -
9) • Vitamins • Calcium and phosphorus analysis in serum and urine • Analysis of urinary calculi Lecture notes and powerpoint presentation
10) • Structure and function of membrane • Analysis of a parameter in blood Lecture notes and powerpoint presentation
11) • Midterm Exam II -
12) • Mitochondria: Bioenergetics • Urine analysis Lecture notes and powerpoint presentation
13) Translation Lecture notes and powerpoint presentation
14) Nucleus: Replication and transcription Lecture notes and powerpoint presentation
15) Final exam -

Sources

Course Notes / Textbooks: Biochemistry (Lippincott Illustrated Reviews Series)Paperback. 6th Edition. Denise R. Ferrier.
Lecturer`s class notes
References: Biochemistry (Lippincott Illustrated Reviews Series)Paperback. 6th Edition. Denise R. Ferrier.
Lecturer`s class notes

Course-Program Learning Outcome Relationship

Learning Outcomes

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5

6

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9

Program Outcomes
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems. 2
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose. 1
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.) 1
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively. 1
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions. 1
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal. 1
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Learning Activity and Teaching Methods

Peer Review
Brainstorming/ Six tihnking hats
Lesson
Lab
Q&A / Discussion
Web Based Learning

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Peer Review
Bilgisayar Destekli Sunum

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Presentation 1 % 10
Midterms 2 % 50
Final 1 % 40
total % 100
PERCENTAGE OF SEMESTER WORK % 60
PERCENTAGE OF FINAL WORK % 40
total % 100

Workload and ECTS Credit Grading

Activities Number of Activities Duration (Hours) Workload
Course Hours 10 15 150
Laboratory 0 30 0
Presentations / Seminar 1 1 1
Midterms 2 3 6
Final 1 2 2
Total Workload 159