Genetics and Bioengineering (English)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

GBE423

Course Name:

Industrial Genetics and Bioengineering II

Course Semester:

Fall

Course Credits:

Theoretical	Practical	Credit	ECTS
4	4	6	12

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi TUĞBA ÖZDAL

Course Lecturer(s):

Dr.Öğr.Üyesi TUĞBA ÖZDAL

Course Assistants:

Course Objective and Content

Course Objectives:

The aim of the course is to provide comprehensive information on biotechnological processes, the basic elements and industrial applications of biocatalysis, bioreaction kinetics and fermented products, the importance of biomass production in genetic engineering and also introduce students the economic and design principles as applied in bioengineering processes and operations, to provide students various stages of plant design such as cost estimations, profitability and feasibility studies, capacity planning, plant location and management, optimum design strategies.

Course Content:

• Describe the application areas and qualifications of bioprocesses technologies
• To be able to evaluate different biotechnological process processes
• To be able to define the principles of biocatalysis
• Development of genetic elements for the purpose of increasing fermentation efficiency
• To be able to define the optimum process parameters of biomass
• To calculate the theoretical efficiency of the current system by using energy and mass balances in biotechnological processes.
• To determine the missing or defective aspects of the existing system and to produce solutions that will eliminate in detail or reduce them insufficiently.
• To be able to distinguish the differences between biotechnological structures

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) • Describe the application areas and qualifications of bioprocess technologies • To evaluate different biotechnological process processes • To be able to define the principles of biocatalysis • To develop genetic factors that will affect the increase of fermentation efficiency To be able to define optimum process parameters in biomass production • To calculate the theoretical efficiency of the current system by using energy and mass balances in biotechnological processes.
2 - Skills
Cognitive - Practical
1) Designing a complex system or product in accordance with the intended objectives, in accordance with realistic constraints and conditions; to this end, to apply current design technologies
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
1) • Information on the global and social impacts of engineering practices on health, environment and safety; awareness of the legal consequences of engineering solutions • To be able to identify the missing or defective aspects of the current system and to produce solutions that will eliminate them or reduce their impact. • To distinguish the differences between biotechnological processes
Competence to Work Independently and Take Responsibility

Lesson Plan

Week	Subject	Related Preparation
1)	Definition, Process Development and Features of Bioprocesses
2)	Biotechnological Processes and Engineering Approaches
3)	Basic Processes of Bioprocesses
4)	Types of Bioreactors
5)	Stoichiometry of Biological Reactions
6)	Stoichiometry of Biological Reactions
7)	Mass and Momentum Transfer in Bioprocesses
8)	Thermodynamics of Biological Reactions
9)	Interim Report of the Projects
10)	Heat Transfer Applications and Sterilization in Bioprocesses
11)	Bioprocess Wastes Removal, Evaluation and Safety Precautions
12)	Bioprocess Design and Economic Analysis
13)	Bioprocess Design and Economic Analysis
14)	Presentaion of the Projects
15)	Final Exam and Project Report

Sources

Course Notes / Textbooks:

Biochemical Engineering Fundamentals
James E. Bailey, David F. Ollis
©1986 | McGraw-Hill Education| ISBN: 978-0070032125

Bioprocess Engineering Principles, 2nd Edition
Pauline M. Doran
©2013 | Elsevier | ISBN: 978-0-12-220851-5

Bioprocess Engineering. Kinetics, Sustainability, and Reactor Design, 2nd Edition
Shijie Liu
©2016 | Elsevier| ISBN: 978-0-444-63783-3

Biyoreaksiyon Mühendisliği, Biyolojik Proseslerin Kinetiği ve Modellenmesi
Mustafa Türker
©2005 | Su Vakfı Yayınları | ISBN: 9756455195

References:

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	3
Program Outcomes
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.	1
2)	The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.
3)	The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)
4)	Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.
5)	Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6)	The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7)	Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.
8)	Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9)	Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10)	Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11)	Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Learning Activity and Teaching Methods

Expression
Brainstorming/ Six tihnking hats
Lesson
Group study and homework
Reading
Problem Solving
Project preparation
Report Writing
Q&A / Discussion
Technical Tour
Application (Modelling, Design, Model, Simulation, Experiment etc.)

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Group project
Presentation
Reporting

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Attendance	15	% 5
Project	1	% 55
Final	1	% 40
total		% 100
PERCENTAGE OF SEMESTER WORK		% 60
PERCENTAGE OF FINAL WORK		% 40
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	13	12	156
Application	13	12	156
Presentations / Seminar	1	2	2
Project	1	45	45
Final	1	3	3
Total Workload			362