Dentistry | |||||
Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 |
Course Code: | DHF117 | ||||||||
Course Name: | Tıbbi Biyoloji ve Genetik | ||||||||
Course Semester: | Fall | ||||||||
Course Credits: |
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Language of instruction: | TR | ||||||||
Course Requisites: | |||||||||
Does the Course Require Work Experience?: | No | ||||||||
Type of course: | Compulsory | ||||||||
Course Level: |
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Mode of Delivery: | Face to face | ||||||||
Course Coordinator : | Dr.Öğr.Üyesi HİLAL EREN GÖZEL | ||||||||
Course Lecturer(s): | |||||||||
Course Assistants: |
Course Objectives: | In our theoretical courses, we start from fundamentals of cell biology and move to the molecular level of cell biology and cellular processes. We aim to teach the importance of the balance between cell division and cell death; disease relevance of cell division and cell death. In addition, we aim to give basic knowledge on other topics such as immunogenetics, genetic technologies, genetic diseases and principles of heredity. Besides, we aim to give disease relevance of these topics. In our practical courses, we aim to enable students to learn and practice fundamental laboratory techniques that are frequently used in Medical Biology and Genetics. When our students start their carrier, we aim to enable them to reach a certain level that they will be able to collaborate on genetics studies, to interpret the results of tests and assays that are used to diagnose a suspected patient with a genetic disease. |
Course Content: | Cellular Structures / Organelles DNA Structure, Function / DNA Replication RNA Structure and Transcriptional Regulation Transcriptional and Post-Transcriptional Regulation Mutations / Mutagenesis Genetic Codes, tRNA, rRNA / Protein Synthesis Review / Problem Solving Post Translational Modifications / Epigenetics Genetic Technologies I Genetic Technologies II Cellular Signalling Pathways Cell Division / Cell Cycle Regulation Cell Death Regulation Review / Problem Solving Human Genome Organisation Genetic Control Mechanisms Chromosome Abnormalities and Disorders Mendel Genetics / Inheritance Patterns Non-Mendelian Genetics Genetic Diseases Review / Problem Solving Cancer Genetics Genetic Counseling Immunogenetics I Immunogenetics II Review / Problem Solving I Review / Problem Solving II |
The students who have succeeded in this course;
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Week | Subject | Related Preparation |
1) | Cellular Structures and Organelles | Bölüm 2,3,4,5-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 1,2- The cell: Molecular Approach,Cooper GM |
2) | DNA Structure and Function/DNA Replication | Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 4, Chapter 6-The cell:Molecular Approach, Cooper GM |
3) | RNA Structure and Transcriptional Regulation | Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 7&8-The cell:Molecular Approach, Cooper GM |
4) | Transcriptional and Post Transcriptional Regulation | Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 7,8- The cell: Molecular Approach, Cooper GM |
5) | Genetic Code/ tRNA, rRNA , Protein Synthesis | Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 7,8- The cell: Molecular Approach, Cooper GM |
6) | Review | Lecture Presentation Slides |
7) | Resmi Tatil | |
8) | 1. Ara Sınav | |
10) | Post translational modifications/Epigenetics | Bölüm 8-Moleküler Hücre Biyolojisi-Hasan Veysi Güneş; Chapter 8,10- The cell: Molecular Approach, Cooper GM |
11) | Mutations/Mutagenesis | Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 6- The cell: Molecular Approach, Cooper GM; |
12) | Genetic Technologies-1 | Bölüm 1-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 4,5- The cell: Molecular Approach, Cooper GM; |
13) | Genetic Technologies-2 | Bölüm 1-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 4,5- The cell: Molecular Approach, Cooper GM; |
14) | Cellular Signaling Pathways | Bölüm 10, Moleküler Hücre Biyolojisi,Hasan Veysi Güneş; Chapter 15, The cell: Molecular Approach, Cooper GM |
15) | Cell division/ Cell Cycle Regulation | Bölüm 11, Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 16, The cell: Molecular Approach, Cooper GM |
16) | 2. Ara Sınav | |
16) | Review | Lecture Presentation Slides |
17) | Regulation of Cell Death | Bölüm 11-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 17- The cell: Molecular Approach, Cooper GM; |
18) | Human Genome Organisation | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
18) | Genetic Control Mechanisms | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
19) | Mendelian Genetics, Inheritance Pattern | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
20) | Non-Mendelian Genetics | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
21) | Chromosome Abnormalities and Disorders | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
22) | Genetic Diseases | Essential Medical Genetics- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith Thompson & Thompson Genetics in Medicine- Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
23) | Review | Lecture presentation slides |
24) | 3. Ara Sınav | |
25) | 3rd Midterm | |
26) | Cancer Genetics | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
27) | Genetic Counseling | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
28) | Immunogenetics-1 | Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
29) | Immunogenetics-2 | Essential Medical Genetics- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith Thompson & Thompson Genetics in Medicine- Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
30) | Review-I | Lecture Presentation Slides |
31) | Review-II | Lecture presentation slides |
32) | Public Holiday |
Course Notes / Textbooks: | Moleküler Hücre Biyolojisi-Hasan Veysi Güneş, İstanbul Tıp HÜCRE:Moleküler Yaklaşım, Cooper Gm, İzmir Tıp Kitapevi Tıbbi Genetiğin Esasları- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith Thompson & Thompson Tıbbi Genetik- Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard |
References: | Moleküler Hücre Biyolojisi-Hasan Veysi Güneş, İstanbul Tıp The Cell: A Molecular Approach-Cooper GM, Sinauer Associates Inc. Essential Medical Genetics- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith Thompson & Thompson Genetics in Medicine- Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard |
Learning Outcomes | 1 |
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Program Outcomes | |||||
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2) ... | |||||
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6) ... |
No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
Program Outcomes | Level of Contribution | |
1) | --- | 3 |
2) | ... | 3 |
3) | .... | 2 |
4) | ... | 4 |
5) | .... | 3 |
6) | ... | 3 |
Field Study | |
Expression | |
Brainstorming/ Six tihnking hats | |
Individual study and homework | |
Lesson | |
Group study and homework | |
Lab | |
Reading | |
Homework | |
Problem Solving | |
Q&A / Discussion | |
Web Based Learning |
Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing) | |
Application |
Semester Requirements | Number of Activities | Level of Contribution |
Committee | 64 | % 0 |
Laboratory | 24 | % 0 |
Midterms | 3 | % 50 |
Final | 1 | % 50 |
total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 50 | |
PERCENTAGE OF FINAL WORK | % 50 | |
total | % 100 |
Activities | Number of Activities | Duration (Hours) | Workload |
Course Hours | 32 | 2 | 64 |
Laboratory | 12 | 2 | 24 |
Midterms | 3 | 8 | 24 |
Final | 1 | 32 | 32 |
Total Workload | 144 |