Genetics and Bioengineering (English)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

GBE205

Course Name:

Microbiology

Course Semester:

Fall

Course Credits:

Theoretical	Practical	Credit	ECTS
2	2	3	5

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi ÖZGE ACAR

Course Lecturer(s):

Dr.Öğr.Üyesi MEHMET KARAKUŞ
Dr.Öğr.Üyesi ŞEYDA ÇALIŞKAN
Prof. Dr. AYŞE DEMET KAYA

Course Assistants:

Course Objective and Content

Course Objectives:

The aim of this course is to provide basics of microbiology and industrial applications for students.

Course Content:

The history of microbiology, today's developments, there are different options.
Archea, Prokaryotes and Eukaryotes Examination of the metabolism of living things, examination of structures at cell level,
Structure of viruses, examination of infectious pathways and different species
Examination of genetic pathways of microorganisms
Applications of microorganisms in genetic engineering and biotechnology
Sterilization, Defenfection, Asepsy and Antisepsis Principles

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) • Describe the scope of microbiology and classify microorganisms
2) • Know bacterial structure, physiology and production environments
3) • be able to identify general features of viruses, fungi and parasites
4) • Know the genetic structures of bacteria and other microorganisms
5) • Know microorganism-host relationships, basic immunologic and immunological response mechanisms
6) • be able to identify antimicrobial agents and resistance mechanisms
7) • Introduction of necessary microorganisms for bioengineering which can produce industrial products
8) • Describe and discuss sterilization and disinfection principles and practices
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
Competence to Work Independently and Take Responsibility

Lesson Plan

Week	Subject	Related Preparation
1)	Discussion of Syllabus
2)	• Classification and naming of microorganisms • History of microbiology to be audited • Introduction to microbiology, history and classification
3)	• Bacterial morphology • Bacterial cell anatomic structure • Bacterial physiology • Bacterial structure and physiology
4)	• Bacterial nuclear materials Bacterial circular DNA • Bacterial DNA replication • Prokaryotic-eukaryotic replication differences • Microorganism genetics 1
5)	• Plasmids • Conjugation • Transduction • Transformation • Bacteriophages • Microorganism genetics 2
6)	• Classification of viruses • Structure of viruses • Viral diseases • General characteristics and classification of viruses
7)	• Classification of fungi • Structure of fungi • Fungal diseases • General characteristics and classification of fungi
8)	Midterm Week
9)	• Classification of parasites • Parasitic diseases • General characteristics and classification of parasites
10)	• Simbiozis and similar life forms • parasitism • Floras, colonization • Microorganism host relationships
11)	• Immune system cells and organs • Antibodies • Natural immunity • Earned immunity • Immunology entry, immune system cells and organs
12)	• opsonization • phagocytosis • NK and IAK cells • Cytokines and others • Immune response mechanisms
13)	• Antimicrobial definition • Classification of antimicrobials • Uses of antimicrobials • Antimicrobial resistance • Antimicrobial agents and resistance mechanisms
14)	• Definition of sterilization and disinfection • Devices and materials used in sterilization and disinfection • Asepsis-antisepsis • Sterilization and disinfection principles and applications
15)	Final Exam

Sources

Course Notes / Textbooks:	Brock Biology of Microorganisms, Michaeal Madigan, John Martinko. Kelly Bewnder. Daniel Buckley. David Steahl. 14th Edition
References:	• Murray & Rosenthal & Pfaller . Medical Microbiology, 7th Edition, Elsevier Saunders, 2012, USA - ISBN: 9780323086929 • Patrick R. Murray, Ellen Jo Barron. Manual of Clinical Microbiology. Edition 8, ASM Press, Washington, • Levinson W. Review of Medical Microbiology and Immunology,13 th Edition , McGraw-Hill Comp.,2014 - ISBN: 9780071818117

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	3	4	5	6	7	8
Program Outcomes
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.	2
2)	The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.	1
3)	The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)	1
4)	Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.	1
5)	Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6)	The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7)	Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.	1
8)	Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.	1
9)	Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10)	Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11)	Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Learning Activity and Teaching Methods

Expression
Brainstorming/ Six tihnking hats
Individual study and homework
Lesson

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Homework

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	5	% 10
Midterms	1	% 40
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	4	56
Homework Assignments	5	1	5
Midterms	1	2	2
Final	1	2	2
Total Workload			65