Genetics and Bioengineering (English)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

GBE303

Course Name:

Physiolgy

Course Semester:

Fall

Course Credits:

Theoretical	Practical	Credit	ECTS
3	2	4	9

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi SEVDA MERT

Course Lecturer(s):

Dr.Öğr.Üyesi ÖZGE ACAR
Dr.Öğr.Üyesi SEVDA MERT
Dr.Öğr.Üyesi ELİF KUBAT ÖKTEM

Course Assistants:

Course Objective and Content

Course Objectives:	The aim of this course is to underline and discuss basic physiology concepts, functional ogranization of the body, relations of cell-organ-system, cell structure and function and functional mechanisms of body systems.
Course Content:	Introduction to Physiology, Cell membrane potentials and transport, Muscle Physiology, Cardiovascular and Circulatory Physiology, Respiratory System Physiology, Neurophysiology, Gastrointestinal System Physiology, Hematology and Endocrine System Physiology, Genitourinary System Physiology

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) The student is able to understand how various systems work to maintain the experience of the human body.
2) The student is able to describe basic physiology.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
1) The student is able to know the underlying mechanisms of disease conditions in relation to systems.
2) The student is able to know when the organization will deviate in relation to the systems.
3) The student is able to learn the physiology of systems
4) The student is able to define the principles of arranging the functions of the systems.
5) The student is able to analyze physiological responses and adaptations to environmental stresses
Competence to Work Independently and Take Responsibility

Lesson Plan

Week	Subject	Related Preparation
1)	• General cell structure and subcellular organelles • Laboratory safety • Clinical laboratories supplies	Lecture notes and powerpoint presentation
2)	• The components of the cell: Carbohydrates • General reaction of amino acids and proteins • Plasma protein electrophoresis	Lecture notes and powerpoint presentation
3)	•Membrane Potential in the Nerve Cell, Distribution of Ions, Resting Membrane potential • Action Potential and Signal Transduction types • Sinaptic transmission • Skeletal Muscles and Contraction Mechanism • Contraction Types in Skeletal Muscles, Energy Requirement • Muscle Reflexes • Smooth Muscle	Lecture notes and powerpoint presentation
4)	• Properties of general sensory receptors and sensory adaptation • Five sensory organs	Lecture notes and powerpoint presentation
5)	• Structure and Functions of the Nervous System • Cortex Structures • Spinal cord • Peripheral Nervous System • Cerebellum, Basal ganglia, Thalamus, Hypothalamus • Limbic System, Brain stem • Autonomic Nervous System • Brain Spinal fluid	Lecture notes and powerpoint presentation
6)	• Classification of Hormans and Mechanisms of Their Impact • Control of the Secretion of Hormones • Pituitary Gland Hormones • Thyroid and Parathyroid Hormones • Adrenal Glands and Hormones • Pancreatic Islet Hormones	Lecture notes and powerpoint presentation
7)	• Heart muscle • Components and Function of the Circulatory System • Heart Cycle • Cardiac Electrical Activity, Electrocardiogram, Electrocardiography • Blood vessels • Blood Flow and Vascular Resistance • Blood pressure • Hypertension and Heart Failure	Lecture notes and powerpoint presentation
8)	Midterm Exam I	-
9)	• Respiratory Function and Structure • Respiratory Biomechanics • Respiratory Function Test • Alveolar Gas Exchange • Movement of Respiratory Gases in Blood • Exercise, High Altitude and Depth Conditions	Lecture notes and powerpoint presentation
10)	• Kidney Functions • Structure of Nephron • Glomerular Filtration • Retinopathy in the tubules, • Normal Urine Properties • Urination and Mortality • The role of kidneys in acid-base regulation • Renin-Angiotensin-Aldosterone System	Lecture notes and powerpoint presentation
11)	Midterm Exam II	-
12)	• Blood plasma • Erythrocytes • Blood Groups • Thrombocytes, Hemostasis, Leukocytes • Immunity • Introduction to Immunology • Immune System Classification • Natural Immune System and its Components • Acquired Immunity and its Elements • T and B lymphocytes • Antigens • Immune System Organs and Cells	Lecture notes and powerpoint presentation
13)	• Structure and Function of Digestion System • Digestion and Absorption • Mouth, Oesophagus, stomach, small bowel, thick intestine • Metabolism • Regulation of feeding • Regulation of body temperature	Lecture notes and powerpoint presentation
14)	• Basic Concepts and Medical Terms in General Physiology .Homeostaz • Negative and Positive Feedback Mechanisms • Body fluid divisions	Lecture notes and powerpoint presentation
15)	Final Exam	-

Sources

Course Notes / Textbooks:	Ders Notlari Guyton A.C., Hall J.E. Tıbbi Fizyoloji, Çeviri Editörleri: Hayrünisa Çavuşoğlu, Berrak Ç.Yeğen. Nobel Tıp Kitabevleri, 11. Baskı, İstanbul, 2007 Human Physiology: An Integrated Approach, Dee Unglaub Silverthorn, 6th Edition, Pearson, 2015, ISBN/ISSN: 978-0321981226
References:	Human Physiology: An Integrated Approach, Dee Unglaub Silverthorn, 6th Edition, Pearson, 2015, ISBN/ISSN: 978-0321981226

Course-Program Learning Outcome Relationship

Learning Outcomes	1	4	2	3	5	6	7
Program Outcomes
1) Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.
2) The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.
3) The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)
4) Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.
5) Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6) The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7) Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.
8) Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9) Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10) Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11) Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Sufficient knowledge in mathematics, science and engineering related to their branches; and the ability to apply theoretical and practical knowledge in these areas to model and solve engineering problems.	2
2)	The ability to identify, formulate, and solve complex engineering problems; selecting and applying appropriate analysis and modeling methods for this purpose.	1
3)	The ability to design a complex system, process, device or product under realistic constraints and conditions to meet specific requirements; the ability to apply modern design methods for this purpose. (Realistic constraints and conditions include such issues as economy, environmental issues, sustainability, manufacturability, ethics, health, safety, social and political issues, according to the nature of design.)	1
4)	Ability to develop, select and use modern techniques and tools necessary for engineering applications; ability to use information technologies effectively.	1
5)	Ability to design experiments, conduct experiments, collect data, analyze and interpret results to examine engineering problems or discipline-specific research topics.
6)	The ability to work effectively in disciplinary and multidisciplinary teams; individual work skill.
7)	Effective communication skills in Turkish oral and written communication; at least one foreign language knowledge; ability to write effective reports and understand written reports, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions.	1
8)	Awareness of the need for lifelong learning; access to knowledge, ability to follow developments in science and technology, and constant self-renewal.
9)	Conform to ethical principles, and standards of professional and ethical responsibility; be informed about the standards used in engineering applications.
10)	Awareness of applications in business, such as project management, risk management and change management; awareness of entrepreneurship, and innovation; information about sustainable development.
11)	Information about the universal and social health, environmental and safety effects of engineering applications and the ways in which contemporary problems are reflected in the engineering field; awareness of the legal consequences of engineering solutions.

Learning Activity and Teaching Methods

Peer Review
Brainstorming/ Six tihnking hats
Lesson
Q&A / Discussion
Web Based Learning

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Peer Review
Bilgisayar Destekli Sunum

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Presentation	1	% 10
Midterms	2	% 50
Final	1	% 40
total		% 100
PERCENTAGE OF SEMESTER WORK		% 60
PERCENTAGE OF FINAL WORK		% 40
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	0	75	0
Presentations / Seminar	1	1	1
Midterms	2	3	6
Final	1	2	2
Total Workload			9