Civil Engineering
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

TLT104

Course Name:

Medical Biology and Genetics

Course Semester:

Spring

Course Credits:

Theoretical	Practical	Credit	ECTS
3	0	3	5

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi FAZİLET ÖZDENOĞLU

Course Lecturer(s):

Course Assistants:

Course Objective and Content

Course Objectives:

This course aims to provide information on the structural and functional properties of nucleic acids (DNA and RNA) and proteins, which are the basic building blocks of life, the conversion of genetic information encoded in nucleotide sequences in genetic materials into protein form (replication-transcription and translation); comprehensive communication package, DNA repair mechanisms, and all genetic diseases.

Course Content:

At the end of this course, the student will be able to:
1. Nucleic acids DNA and RNA structure- DNA - RNA types
2. Central birth- replication- transcription- translation
3. Genetic terms- genetic concepts
4. Gene level mutations and chromosomal mutations
5. DNA repair mechanisms
6. Mutagens
6. Epigenetics and genetic diseases

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Nucleic acids explain the structure of DNA and RNA
2) Gains information about central genesis- replication- transcription- translation
3) Explains gene level mutations and chromosomal mutations.
4) Explain DNA repair mechanisms and mutagens
5) Explains epigenetics and genetic diseases.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
1) Knows genetic terms
Competence to Work Independently and Take Responsibility
1) It aims to train technicians who can actively participate in discussions about genetics and science, evaluate these discussions, and consciously evaluate scientific information and applications they will encounter in daily life.

Lesson Plan

Week	Subject	Related Preparation
1)	Overview of course and course content Introduction to Medical Biology and Genetics	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
2)	Structure of nucleic acids DNA and RNA	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
3)	DNA replication	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
4)	Transcription in Prokaryotes	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
5)	Ökaryotlarda Transkripsiyon	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
6)	Translasyon	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
7)	Genetic Concepts, terms	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
8)	MIDTERM EXAM
9)	Mutations	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
10)	mutagens	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
11)	DNA Repair Mechanisms	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
12)	Epigenetics	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
13)	Genetic Diseases	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
13)	Epigenetics Cancer Mechanism
14)	Chromosomal Diseases	Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek Medical Genetics –Thompson Mehmet Kaşifoğlu
15)	final exam

Sources

Course Notes / Textbooks:	Ders Notları Tıbbi Genetiğin Esasları Prof. Dr. Uğur Özbek, 2014 Tıbbi Genetik –Thompson Mehmet Kaşifoğlu, 2019
References:	Lecture Notes Fundamentals of Medical Genetics Prof. Dr. Uğur Özbek, 2014 Medical Genetics –Thompson Mehmet Kaşifoğlu, 2019

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	4	5	6	3	7
Program Outcomes
1) Adequate knowledge in mathematics, science and engineering subjects pertaining to the relevant discipline; ability to use theoretical and applied information in these areas to model and solve engineering problems.
2) Ability to identify, formulate, and solve complex engineering problems; ability to select and apply proper analysis and modelling methods for this purpose.
3) Ability to design a complex system, process, device or product under realistic constraints and conditions, in such a way so as to meet the desired result; ability to apply modern design methods for this purpose. (Realistic constraints and conditions may include factors such as economic and environmental issues, sustainability, manufacturability, ethics, health, safety isuues, and social and political issues according to the nature of the design.)
4) Ability to devise, select, and use modern techniques and tools needed for engineering practice; ability to employ information technologies effectively.
5) Ability to design and conduct experiments, gather data, analyse and interpret results for investigating engineering problems.
6) Ability to work efficiently in intra-disciplinary and multi-disciplinary teams; ability to work individually.
7) Ability to communicate effectively i Turkish, both orally and in writing; knowledge of a minimum of one foreign language.
8) Recognition of the need for lifelong learning; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.
9) Awareness of professional and ethical responsibility.
10) Information about business life practices such as project management, risk management, and change management; awareness of entrepreneurship, innovation, and sustainable development.
11) Knowledge about contemporary issues and the global and societal effects of engineering practices on health, environment, and safety; awareness of the legal consequences of engineering solutions.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Adequate knowledge in mathematics, science and engineering subjects pertaining to the relevant discipline; ability to use theoretical and applied information in these areas to model and solve engineering problems.
2)	Ability to identify, formulate, and solve complex engineering problems; ability to select and apply proper analysis and modelling methods for this purpose.
3)	Ability to design a complex system, process, device or product under realistic constraints and conditions, in such a way so as to meet the desired result; ability to apply modern design methods for this purpose. (Realistic constraints and conditions may include factors such as economic and environmental issues, sustainability, manufacturability, ethics, health, safety isuues, and social and political issues according to the nature of the design.)
4)	Ability to devise, select, and use modern techniques and tools needed for engineering practice; ability to employ information technologies effectively.
5)	Ability to design and conduct experiments, gather data, analyse and interpret results for investigating engineering problems.
6)	Ability to work efficiently in intra-disciplinary and multi-disciplinary teams; ability to work individually.
7)	Ability to communicate effectively i Turkish, both orally and in writing; knowledge of a minimum of one foreign language.
8)	Recognition of the need for lifelong learning; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.
9)	Awareness of professional and ethical responsibility.
10)	Information about business life practices such as project management, risk management, and change management; awareness of entrepreneurship, innovation, and sustainable development.
11)	Knowledge about contemporary issues and the global and societal effects of engineering practices on health, environment, and safety; awareness of the legal consequences of engineering solutions.

Learning Activity and Teaching Methods

Expression
Lesson
Q&A / Discussion

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 40
Final	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Workload
Course Hours	16	48
Study Hours Out of Class	15	49
Homework Assignments	7	25
Quizzes	8	19
Midterms	1	1
Final	1	1
Total Workload		143