Dentistry
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

DHF321

Course Name:

Pathology

Course Semester:

Fall

Course Credits:

Theoretical	Practical	Credit	ECTS
4	2	5	6

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi DİDAR AYGÜN GÜLHAN

Course Lecturer(s):

Course Assistants:

Course Objective and Content

Course Objectives:

The purpose of this course is to provide general information about pathology of human body. Moreover, this Lecture aimst teach the pathology laboratory functioning and practices and general terms in the pathology. During the lectures, students will be identify the pathology departments and will know the routine function, organization, authorization and responsibility of pathology.

Course Content:

• To identify the disease and etiology terms, will learn the basic pathology terms to understand the clinical and pathological diagnosis in the pathology report and to know cell injury mechanism and strıctural changes of tissue and organ.
• To define a knowledge about the work safely in the laboratory and the occupational risks
• To learn the medical waste disposal process and the basic functioning of archive and storage.
• To identify a knowledge about the tools, materials and chemicals that are used in laboratory
• To have knowledge of these chemicals properties and the basic rules of their safety usage.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Having basic level theoretical and practical knowledge supported by textbooks, application tools and other resources containing current information in the field based on the qualifications gained at the secondary level.
2 - Skills
Cognitive - Practical
1) To gain the ability to use the basic theoretical and applied knowledge acquired in the field in the same field at a further education level or in a field at the same level. - Ability to interpret and evaluate data, identify problems, analyze data, and develop evidence-based solutions by using the basic knowledge and skills in the field.
3 - Competences
Communication and Social Competence
1) - To be able to convey his / her thoughts at the level of basic knowledge and skills in written and verbal communication. - To be able to share their thoughts and solution suggestions on issues related to the field with experts and non-experts. - To be able to follow information in his / her field and communicate with colleagues by using a foreign language at least at A2 General Level of European Language Portfolio. - Information and communication technologies with computer software at least at the European Computer Driving License Basic Level required by the field
Learning Competence
1) To be able to evaluate the basic knowledge and skills acquired in the field with a critical approach, to determine and meet the learning needs. - To be able to direct his education to a further education level in the same field or to a profession at the same level. - Gained awareness of lifelong learning.
Field Specific Competence
1) Having social, scientific, cultural and ethical values in the stages of collecting, applying and announcing the results of the field. - To have sufficient awareness about the universality of social rights, social justice, quality and cultural values and environmental protection, occupational health and safety.
Competence to Work Independently and Take Responsibility
1) - To be able to conduct a basic level study independently in the field. - Taking responsibility as a team member to solve unforeseen and complex problems encountered in applications related to the field. - To be able to carry out activities for the development of employees under their responsibility within the framework of a project.

Lesson Plan

Week	Subject	Related Preparation
1)	Pathology laboratory presentation. Laboratory operations, cell, tissue, organ definitions. Biopsy and biopsy types. Fixation, tissue follow-up, cross-section and staining procedures, archive and laboratory security.
2)	Basic terminology in pathology, definition of disease and causes of disease
3)	Cellular adaptation- hyperplasia, hypertrophy, atrophy, metaplasia, cell injury
4)	Cell death, necrosis and types of necrosis, apoptosis.
5)	Intracellular deposits: Carbohydrate, protein, fat, pigment mineral metabolism disorders
6)	Physiopathology of inflammation, Acute and chronic inflammation: Definitions, cells, causes and consequences.
7)	Chemical mediators of inflammation I.
8)	Chemical mediators of inflammation II.
9)	Introduction to immune system, basic concepts in immunity, cells involved in immune response
10)	Immune system pathology, hypersensitivity reactions, immunodeficiency diseases
11)	Continuation of immune system pathology, autoimmune disease
12)	Tissue regeneration and repair: Cell proliferation control, growth factors, repair mechanisms.
13)	Wound healing. Primary and secondary recovery. Factors that delay wound healing, pathological wound healing. Definition of stem cells, stem cells.
14)	Transplantation pathology, excretion reactions and morphology of excretion reactions, methods to increase graft survival,
15)	Fluid electrolyte balance, distribution of body fluids, tasks of water and electrodes, fluid movements between vessels and tissues, fluid movements between tissues and cells.
16)	Fluid-electrolyte balance disorders, edema, hyperemia-congestion, hemorrhage, shock pathophysiology, types and stages of shock, changes in shock organs.
17)	Fluid electrolyte balance disorders continuation, thrombosis, embolism, ischemia, infarction
18)	Neoplasia; Nomenclature of tumors, Benin and malignant tumor characteristics, TNM system and grading in Mlin tumors.
19)	Neoplasia persists; Epidemiology of tumor, tumor etiology
20)	Neoplasia, continued: Mechanisms of carcinogenesis, protooncogenes, tumor suppressor genes, genes regulating apoptosis, genes responsible for DNA repair.
21)	Neoplasia, continued: Paths of metastasis of malignant tumors. Angiogenesis in tumor spread. Paraneoplasic syndromes, Tumor markers.
22)	Neoplasia, continued: Diagnostic methods in neoplasms. Radiological, biochemical, cytological, histopathological investigations. Short treatment methods.
23)	Neoplasia, continued: Tumors in organs and tissues, Premalin lesions, benign and malignant tumors of epithelial tissue-mesenchymal tissue-nerve tissue
24)	Oral pathology: Inflammatory lesions of the oral region and pulpar, periapical, peridontal region. Osteomyelitis.
25)	Oral pathology: Benign and malignant tumors
26)	Oral pathology: Cystic lesions of the jaw and neck
27)	Oral pathology: Odontogenic tumors
28)	Oral pathology: Diseases of salivary gland

Sources

Course Notes / Textbooks:	YOK
References:	Robbinsand Cotran Pathologic Basis of Dease, Ninth Edition, 2015 Oral Pathology Clinical Pathologic Correlations, Sixth Edition, 2012 Oral Pathology for the Dental Hygienist, sixth Edition, 2014 Clinical Oral Medicine and Pathology, 2009 Surgical Pathology of the Head and Neck, Third Edition, 2009 Modern Surgical Pathology, Second Edition, 2009 DUS patoloji kitabı, TUSEM YAYINLARI 2012.

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	3	4	5	6
Program Outcomes
1) ---
2) ...
3) ....
4) ...
5) ....
6) ...

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	---	2
2)	...	3
3)	....	2
4)	...	3
5)	....	2
6)	...	1

Learning Activity and Teaching Methods

Expression
Brainstorming/ Six tihnking hats
Lesson
Lab

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Oral Examination
Application
Observation
Bilgisayar Destekli Sunum

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	3	% 40
Final	1	% 50
Kanaat Notu	1	% 10
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Laboratory	1	10	10
Midterms	3	40	120
Final	1	50	50
Total Workload			180