PhD in Nutrition and Dietetics with a master's degree
PhD	TR-NQF-HE: Level 8	QF-EHEA: Third Cycle	EQF-LLL: Level 8

General course introduction information

Course Code:

BDY652

Course Name:

Oxidative Stress and Antioxidant Vitamins and Minerals

Course Semester:

Fall

Course Credits:

Theoretical	Practical	Credit	ECTS
3	0	3	15

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Department Elective

Course Level:

PhD

TR-NQF-HE:8. Master`s Degree

QF-EHEA:Third Cycle

EQF-LLL:8. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi AHMET MURAT GÜNAL

Course Lecturer(s):

Course Assistants:

Course Objective and Content

Course Objectives:	To have knowledge about free radicals, oxidative stress and the role of vitamins and minerals in the defense mechanisms of the human body.
Course Content:	Free radicals, oxidative stress and the role of vitamins and minerals in the defense mechanisms of the human body.

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) To have knowledge about what free radicals are and how they are formed.
2) To have knowledge about what reactive oxygen species (ROS) are and how they are formed.
3) To have knowledge about what reactive nitrogen species (RNS) are and how they are formed.
4) To have knowledge about what antioxidant defense mechanisms are and how they are formed.
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) To be able to browse the current publications on the subject.
Field Specific Competence
Competence to Work Independently and Take Responsibility

Lesson Plan

Week	Subject	Related Preparation
1)	What are free radicals and how are they formed?	none
2)	What are reactive oxygen species (ROS) and how are they formed?	none
3)	What are reactive nitrogen species (RNS) and how are they formed?	none
4)	Energy Production Pathways: Glycolysis	none
5)	Energy Production Pathways: The Citric Acid Cycle	none
6)	Energy Production Pathways: Electron Transfer System	none
7)	Pentose-Phosphate Pathway	none
8)	Enzymatic Antioxidants: Superoxide Dismutase (SOD), Catalase	none
9)	Enzymatic Antioxidants: Glutathione Peroxidase, Glutathione Reductase	none
10)	Non-enzymatic antioxidants: glutathione, lipoic acid, coenzyme Q, L-arginine, melatonin, uric acid, bilirubin, metal-binding proteins	none
11)	Nutritional antioxidants: selenium, zinc, manganese, omega 3, beta carotene, tocopherol, ascorbic acid.	none
12)	Student presentations	none
13)	Student presentations	none
14)	Student presentations	none

Sources

Course Notes / Textbooks:	Champe, P. C., Harvey, R. A., & Ferrier, D. R. (2005). Biochemistry. Lippincott Williams & Wilkins.
References:	Champe, P. C., Harvey, R. A., & Ferrier, D. R. (2005). Biochemistry. Lippincott Williams & Wilkins.

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	3	4	5
Program Outcomes
1) To be able to defend original ideas in discussing the issues in the field, to analyze and develop social relations and norms that direct these relations with a critical point of view
1) Increase decision-making ability by developing rational solutions with creative and critical thinking method to new developments related to the field and possible problems.
2) To acquire the ability to develop, authenticate and deepen the level of expertise by researching, discussing and discussing more sophisticated and advanced information in an up-to-date and original manner in relation to the graduate education that the student has received.
3) Be able to evaluate and use new information in the field with a systematic approach.
5) To develop multidisciplinary study skills and to provide practical approaches to solve interdisciplinary problems and to be a leader in the team here.
7) to contribute to the solution of social, scientific, cultural and ethical problems encountered in the issues related to the moment, to make good use of the strategic decision-making processes in the solution of these problems and to contribute to the society in which it lives

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	To be able to defend original ideas in discussing the issues in the field, to analyze and develop social relations and norms that direct these relations with a critical point of view
1)	Increase decision-making ability by developing rational solutions with creative and critical thinking method to new developments related to the field and possible problems.
2)	To acquire the ability to develop, authenticate and deepen the level of expertise by researching, discussing and discussing more sophisticated and advanced information in an up-to-date and original manner in relation to the graduate education that the student has received.
3)	Be able to evaluate and use new information in the field with a systematic approach.
5)	To develop multidisciplinary study skills and to provide practical approaches to solve interdisciplinary problems and to be a leader in the team here.
7)	to contribute to the solution of social, scientific, cultural and ethical problems encountered in the issues related to the moment, to make good use of the strategic decision-making processes in the solution of these problems and to contribute to the society in which it lives

Learning Activity and Teaching Methods

Expression
Individual study and homework
Lesson
Homework
Q&A / Discussion

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Homework
Presentation

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	1	% 20
Presentation	1	% 20
Final	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Presentations / Seminar	1	10	10
Homework Assignments	1	5	5
Final	1	10	10
Total Workload			67