Dentistry (English)
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

DENT109

Course Name:

Medical Organic Chemistry

Course Semester:

Fall

Course Credits:

Theoretical	Practical	Credit	ECTS
2	0	2	2

Language of instruction:

Course Requisites:

Does the Course Require Work Experience?:

Yes

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi HADI KARIMKHAN

Course Lecturer(s):

Course Assistants:

Course Objective and Content

Course Objectives:

Evaluate the chemical reactions occurring in living organisms and in laboratory and the properties of organic reactions.

Course Content:

This course contains;
1. Introduction to organic chemistry, C-C bonding
2. C-heteroatom bonding and properties
3. Alkanes and radicalic reactions
4. Alkenes
5. Elimination and addition reactions
6. Alkines and cycloalkanes
7. Aromatic structure and aromatic substitution reactions
8. Stereochemistry
9. Alkyl halogenures and nucleophylic substiyution reactions
10. Acid-base properties, alkohols and phenols
11. Carbonyl compounds, aldehydes and ketones
12. Nucleophylic addition to carbonyl groups
13. α-Addition to carbonyl groups
14. Carboxylic acids and their derivatives, amines and their reactions
15. Amino acids and proteins, carbohydrates, nucleic acids : DNA and RNA .

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
1) 1. will be able to categorize organic compounds.
2) 1.1. distinguishes alkanes, alkenes and alkynes.
3) 1.2. illustrates alkylhalogenures, alcohols, phenols, ethers and amines.
4) 1.3. recognizes carboxylic acids, esters, acide halogenures, acide anhydrides and amides.
5) 1.4. illustrates aldehydes, ketones and their derivatives.
6) 2. will be able to interpret the reactions of compounds in different organic categories.
7) 2.1. demonstrates elimination reactions.
8) 2.2. demonstrates substitution reactions.
9) 2.3. explains mechanisms of organic reactions.
10) 3. will be able to define isomerism.
11) 3.1.defines structural isomerism.
12) 3.2.defines fonctional group isomerism
13) 3.3. defines geometric isomerism.
14) 4. will be classified natural and synthetic polymers.
15) 4.1. illustrated the polymers derived from sugars.
16) 4.2. classified the polimers derived from aminoacids or nucleic acids.
17) 4.3. distinguishes synthetic polymers.
Field Specific Competence
Competence to Work Independently and Take Responsibility

Lesson Plan

Week	Subject	Related Preparation
1)	Introduction Organic Chemistry in Medicine	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
2)	Aromatic Compounds	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
3)	Alkanes, Alkenes, Alkynes, cycloalkanes, Aromatic reactions	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
4)	Stereoisomerism	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
5)	Functional Groups	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
6)	Reactions	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
7)	Amino Acids	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
8)	Midterm	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
9)	Proteins	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
10)	DNA Yapisi ve Repli̇kasyon	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
11)	Structure and function of DNA	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
12)	Carbohydrates	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
13)	Lipids	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
14)	Enzymes I	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
15)	Enzymes II	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry
16)	Final Exam	1. Organic Chemistry 2. Harper's Illustrated Biochemistry 3. Lehninger Principles of Biochemistry

Sources

Course Notes / Textbooks:

1. Organik Kimya
Yazarlar: Graham Solomons
Yayınevi: Literatür Yayıncılık - 11.Baskı (2016)
ISBN: 9789750407390

2. Organic Chemistry
Yazarlar: T. W. Graham Solomons , Craig B. Fryhle , Scott A. Snyder
Yayınevi: Wiley - 2017
ISBN: 9781119248972

3. Harper Biyokimya
Yazarlar: Murray, Bender, Weil, Botham, Kennely, Rodwell
Yayınevi: Nobel Tıp Kitabevi - 2015
ISBN: 9786053351542

4. Harper's Illustrated Biochemistry
Yazarlar: Robert K. Murray, David A Bender, Kathleen M. Botham, Peter J. Kennelly, Victor W. Rodwell and P. Anthony Weil
Yayınevi: McGraw –Hill; 29th Edition (2015)
ISBN: 978 - 0- 07-176576-3

5. Lehninger Principles of Biochemistry
Yazarlar: David L. Nelson and Michael M. Cox
Yayınevi: W. H. Freeman; 6th Edition (2012)
ISBN: 10: 071677108X

6. Lehninger - Biyokimyanın İlkeleri
Yazarlar:Y. Murat Elçin, David Nelson , Michael M. Cox
Yayınevi: Palme Yayınevi - Akademik Kitaplar - 2018
ISBN: 9786053551393

References:

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Program Outcomes
1) Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2) Use of advanced theoretical and practical knowledge within the field. -Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
3) - Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field. - Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data. -Organize and implement project and activities for social environment with a sense of social responsibility. -Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level. -Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level softwar
4) -Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach. -Determine learning needs and direct the learning. -Develop positive attitude towards lifelong learning.
5) Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field. - Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
6) Conduct studies at an advanced level in the field independently. - Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field. - Planning and managing activities towards the development of subordinates in the framework of a project.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2)	Use of advanced theoretical and practical knowledge within the field. -Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
3)	- Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field. - Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data. -Organize and implement project and activities for social environment with a sense of social responsibility. -Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level. -Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level softwar
4)	-Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach. -Determine learning needs and direct the learning. -Develop positive attitude towards lifelong learning.
5)	Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field. - Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
6)	Conduct studies at an advanced level in the field independently. - Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field. - Planning and managing activities towards the development of subordinates in the framework of a project.

Learning Activity and Teaching Methods

Expression
Brainstorming/ Six tihnking hats
Individual study and homework
Lesson
Group study and homework
Lab
Homework
Q&A / Discussion
Application (Modelling, Design, Model, Simulation, Experiment etc.)

Assessment & Grading Methods and Criteria

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 50
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	16	2	32
Study Hours Out of Class	16	2	32
Homework Assignments	16	1	16
Midterms	1	1	1
Final	1	0	0
Total Workload			81