ISTANBUL OKAN UNIVERSITY INFORMATION PACKAGE / COURSE CATALOGUE
DHF117 Medical Biology and Genetics
Istanbul Okan University
Degree Programs
Dentistry
General Information For Students
Diploma SupplementErasmus Policy Statement
National Qualifications
Dentistry
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

General course introduction information

Course Code: DHF117
Course Name: Medical Biology and Genetics
Course Semester: Fall
Course Credits:
Theoretical Practical Credit ECTS
4 2 5 6
Language of instruction: TR
Course Requisites:
Does the Course Require Work Experience?: No
Type of course: Compulsory
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator : Dr.Öğr.Üyesi HİLAL EREN GÖZEL
Course Lecturer(s):
Course Assistants:

Course Objective and Content

Course Objectives: In our theoretical courses, we start from fundamentals of cell biology and move to the molecular level of cell biology and cellular processes. We aim to teach the importance of the balance between cell division and cell death; disease relevance of cell division and cell death. In addition, we aim to give basic knowledge on other topics such as immunogenetics, genetic technologies, genetic diseases and principles of heredity. Besides, we aim to give disease relevance of these topics.
In our practical courses, we aim to enable students to learn and practice fundamental laboratory techniques that are frequently used in Medical Biology and Genetics.
When our students start their carrier, we aim to enable them to reach a certain level that they will be able to collaborate on genetics studies, to interpret the results of tests and assays that are used to diagnose a suspected patient with a genetic disease.
Course Content: Cellular Structures / Organelles
DNA Structure, Function / DNA Replication
RNA Structure and Transcriptional Regulation
Transcriptional and Post-Transcriptional Regulation
Mutations / Mutagenesis
Genetic Codes, tRNA, rRNA / Protein Synthesis
Review / Problem Solving
Post Translational Modifications / Epigenetics
Genetic Technologies I
Genetic Technologies II
Cellular Signalling Pathways
Cell Division / Cell Cycle Regulation
Cell Death Regulation
Review / Problem Solving
Human Genome Organisation
Genetic Control Mechanisms
Chromosome Abnormalities and Disorders
Mendel Genetics / Inheritance Patterns
Non-Mendelian Genetics
Genetic Diseases
Review / Problem Solving
Cancer Genetics
Genetic Counseling
Immunogenetics I
Immunogenetics II
Review / Problem Solving I
Review / Problem Solving II

Learning Outcomes

The students who have succeeded in this course;
Learning Outcomes
1 - Knowledge
Theoretical - Conceptual
1) To teach the fundamental topics of Molecular Biology and Genetics discipline
2 - Skills
Cognitive - Practical
1) Encouraging students to - find and follow reliable websites that contain videos related to lecture topics - find and follow reliable websites that contain current news related to scientific developments
3 - Competences
Communication and Social Competence
Learning Competence
1) Enabling students to establish correct connection between the lecture topics that are covered during the year Enabling students to establish cause and effect relationship on a cellular and genetics basis
Field Specific Competence
Competence to Work Independently and Take Responsibility

Lesson Plan

Week Subject Related Preparation
1) Cellular Structures and Organelles Bölüm 2,3,4,5-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 1,2- The cell: Molecular Approach,Cooper GM
2) DNA Structure and Function/DNA Replication Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 4, Chapter 6-The cell:Molecular Approach, Cooper GM
3) RNA Structure and Transcriptional Regulation Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 7&8-The cell:Molecular Approach, Cooper GM
4) Transcriptional and Post Transcriptional Regulation Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 7,8- The cell: Molecular Approach, Cooper GM
5) Genetic Code/ tRNA, rRNA , Protein Synthesis Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 7,8- The cell: Molecular Approach, Cooper GM
6) Review Lecture Presentation Slides
7) Resmi Tatil
8) 1. Ara Sınav
10) Post translational modifications/Epigenetics Bölüm 8-Moleküler Hücre Biyolojisi-Hasan Veysi Güneş; Chapter 8,10- The cell: Molecular Approach, Cooper GM
11) Mutations/Mutagenesis Bölüm 8-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 6- The cell: Molecular Approach, Cooper GM;
12) Genetic Technologies-1 Bölüm 1-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 4,5- The cell: Molecular Approach, Cooper GM;
13) Genetic Technologies-2 Bölüm 1-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 4,5- The cell: Molecular Approach, Cooper GM;
14) Cellular Signaling Pathways Bölüm 10, Moleküler Hücre Biyolojisi,Hasan Veysi Güneş; Chapter 15, The cell: Molecular Approach, Cooper GM
15) Cell division/ Cell Cycle Regulation Bölüm 11, Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 16, The cell: Molecular Approach, Cooper GM
16) 2. Ara Sınav
16) Review Lecture Presentation Slides
17) Regulation of Cell Death Bölüm 11-Moleküler Hücre Biyolojisi, Hasan Veysi Güneş; Chapter 17- The cell: Molecular Approach, Cooper GM;
18) Human Genome Organisation Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
18) Genetic Control Mechanisms Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
19) Mendelian Genetics, Inheritance Pattern Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
20) Non-Mendelian Genetics Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
21) Chromosome Abnormalities and Disorders Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
22) Genetic Diseases Essential Medical Genetics- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith Thompson & Thompson Genetics in Medicine- Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
23) Review Lecture presentation slides
24) 3. Ara Sınav
25) 3rd Midterm
26) Cancer Genetics Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
27) Genetic Counseling Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
28) Immunogenetics-1 Tıbbi Genetiğin Esasları, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Tıbbi Genetik, Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard; Essential Medical Genetics, Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith; Thompson & Thompson Genetics in Medicine, Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
29) Immunogenetics-2 Essential Medical Genetics- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith Thompson & Thompson Genetics in Medicine- Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard
30) Review-I Lecture Presentation Slides
31) Review-II Lecture presentation slides
32) Public Holiday

Sources

Course Notes / Textbooks: Moleküler Hücre Biyolojisi-Hasan Veysi Güneş, İstanbul Tıp

HÜCRE:Moleküler Yaklaşım, Cooper Gm, İzmir Tıp Kitapevi

Tıbbi Genetiğin Esasları- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith

Thompson & Thompson Tıbbi Genetik- Robert L. Nussbaum , Roderick R. McInnes , Huntington F. Willard
References: Moleküler Hücre Biyolojisi-Hasan Veysi Güneş, İstanbul Tıp

The Cell: A Molecular Approach-Cooper GM, Sinauer Associates Inc.

Essential Medical Genetics- Edward S. Tobias, Michael Connor, Malcolm Ferguson-Smith

Thompson & Thompson Genetics in Medicine- Robert L. Nussbaum , Roderick R. McInnes ,Huntington F. Willard

Course-Program Learning Outcome Relationship

Learning Outcomes

1

2

3
Program Outcomes
1) ---
2) ...
3) ....
4) ...
5) ....
6) ...

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) --- 3
2) ... 3
3) .... 2
4) ... 4
5) .... 3
6) ... 3

Learning Activity and Teaching Methods

Field Study
Expression
Brainstorming/ Six tihnking hats
Individual study and homework
Lesson
Group study and homework
Lab
Reading
Homework
Problem Solving
Q&A / Discussion
Web Based Learning

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Application

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Committee 64 % 0
Laboratory 24 % 0
Midterms 3 % 50
Final 1 % 50
total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
total % 100

Workload and ECTS Credit Grading

Activities Number of Activities Duration (Hours) Workload
Course Hours 32 2 64
Laboratory 12 2 24
Midterms 3 8 24
Final 1 32 32
Total Workload 144