Nutrition and Dietetics
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

General course introduction information

Course Code:

BES222

Course Name:

Nutritional Biochemistry II

Course Semester:

Spring

Course Credits:

Theoretical	Practical	Credit	ECTS
2	0	2	4

Language of instruction:

TR-EN

Course Requisites:

Does the Course Require Work Experience?:

Type of course:

Compulsory

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator :

Dr.Öğr.Üyesi KÜBRA DERYA İPEK

Course Lecturer(s):

Dr.Öğr.Üyesi BERRAK DUMLUPINAR

Course Assistants:

Course Objective and Content

Course Objectives:

This lecture covers the most areas of Biochemistry. Nutritional biochemistry includes the biochemical mechanisms of nutrition and the metabolism of macronutrient and micronutrients. The basic topics of nutritional biochemistry are the biochemical endocrinology, the structure and metabolism of purine/pyrimidine, DNA and RNA, effects of ROS and antioxidants and synthesis of eicosanoids and neurotransmitter.

Course Content:

Purines, Pyrimidines, Nucleosides & Nucleotides: Structure and Function
Purine & Pyrimidine: Digestion & Metabolism
DNA: Organization, Replication & Repair
RNA: Synthesis & Postranscriptional Modifications
Protein: Synthesis & Posttranslational Modifications
Special proteins I: Enzymes, Plasma Proteins & Immunoglobulins
Specific proteins II: Hemoglobin & Myoglobin
Porphyrins & Bile acids: Structure and Metabolism
Hormones I: Classification
Hormones II: Mechanism of action
Hormones III: Regulation of Fuel Metabolism with Insulin & Contra-regulator Hormones
Free Radicals and Antioxidant Nutrients

Learning Outcomes

The students who have succeeded in this course;

Learning Outcomes

1 - Knowledge
Theoretical - Conceptual
1) Can compare the structure and synthesis of purines and pyrimidines
2) Can describe the structure and synthesis of DNA and RNA
3) Can describe protein synthesis
4) Can explain the properties of enzymatic reactions
5) Can explain the importance of plasma proteins
6) Can describe general properties, structure and functions of hormones
7) Can understand the changes in metabolism in the case of hunger and toughness
8) Can understand biochemical mechanisms and metabolism of nutrition
9) Describe the effects of reactive oxygen species and antioxidants
10) Can explain antioxidant-containing nutrients and their effects
2 - Skills
Cognitive - Practical
3 - Competences
Communication and Social Competence
Learning Competence
Field Specific Competence
Competence to Work Independently and Take Responsibility

Lesson Plan

Week	Subject	Related Preparation
1)	Purines, Pyrimidines, Nucleosides & Nucleotides: Structure and Function	Analyze the syllabus Homework: Assigned reading for the next class sessions
2)	Purine & Pyrimidine: Digestion & Metabolism	Homework: Assigned reading for the next class sessions
3)	DNA: Organization, Replication & Repair	Homework: Assigned reading for the next class sessions
4)	RNA: Synthesis & Postranscriptional Modifications	Homework: Assigned reading for the next class sessions
5)	Protein: Synthesis & Posttranslational Modifications	Homework: Assigned reading for the next class sessions
6)	Special proteins I: Enzymes, Plasma Proteins & Immunoglobulins	Homework: Assigned reading for the next class sessions
7)	Specific proteins II: Hemoglobin & Myoglobin	Work for the examination
8)	MIDTERM EXAMINATION
9)	Porphyrins & Bile acids: Structure and Metabolism	Homework: Assigned reading for the next class sessions
10)	Hormones I: Classification	Homework: Assigned reading for the next class sessions
11)	Hormones II: Mechanism of action	Homework: Assigned reading for the next class sessions
12)	Hormones III: Regulation of Fuel Metabolism with Insulin & Contra-regulator Hormones	Homework: Assigned reading for the next class sessions
13)	Micronutrients: Vitamins and Minerals	Homework: Assigned reading for the next class sessions
14)	Free Radicals and Antioxidant Nutrients	Work for the final exam

Sources

Course Notes / Textbooks:

1. Medical Biochemistry. 4th. John Baynes, Marek H. Dominiczak.
2. Marks' Basic Medical Biochemistry: A Clinical Approach. 4th Edition. Alisa Peet, Michael A. Lieberman ve Allan Marks.
3. Harper's Illustrated Biochemistry, 30th Edition. Victor W. Rodwell, David Bender, Kathleen M. Botham, Peter J. Kennelly and P. Anthony Weil.
4. Lehninger Principles of Biochemistry. 6th Edition. David L. Nelson and Michael M. Cox.
5. Biochemistry (Lippincott Illustrated Reviews Series)Paperback. 6th Edition. Denise R. Ferrier.
6. Color Atlas of Biochemistry. 2nd Edition. Jan Koolman and Klaus-Heinrich Roehm.

References:

Course-Program Learning Outcome Relationship

Learning Outcomes	1	2	3	4	5	6	7	8	9	10
Program Outcomes
1) Graduates have the knowledge of attaining scientific knowledge in the field, monitoring, evaluating and applying current literature.
2) Graduates provide preventive health education for individual, family and community by using the information obtained in health field.
3) Graduates take responsibility as individuals and team members to solve complex and unforeseen problems encountered in the field of practice.
5) Graduates evaluates advanced knowledge and skills in the field of health with a critical approach.
6) Graduates transfer information and solution proposal for problems to people and institutions concerned about health field in written and verbally; listen to the thoughts, expectations and expectations of the people and institutions concerned.
7) Graduates become a role model for colleagues and society through Professional identity.
8) Graduates are competent enough to understand the anatomy, physiological functions and behavior of healthy individuals and/or the patients; it is empowering to understand the relationship between the individual's health and the physical and social environment.
9) As an individual, he acts in accordance with laws, regulations, legislation and professional codes of ethics regarding his duties, rights and responsibilities.
10) Cooperate with persons from related disciplines and act in accordance with social, scientific, cultural and ethical values at the stages of data collection, interpretation, application and announcement of results related to the health field.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Graduates have the knowledge of attaining scientific knowledge in the field, monitoring, evaluating and applying current literature.	4
2)	Graduates provide preventive health education for individual, family and community by using the information obtained in health field.	4
3)	Graduates take responsibility as individuals and team members to solve complex and unforeseen problems encountered in the field of practice.	3
5)	Graduates evaluates advanced knowledge and skills in the field of health with a critical approach.	4
6)	Graduates transfer information and solution proposal for problems to people and institutions concerned about health field in written and verbally; listen to the thoughts, expectations and expectations of the people and institutions concerned.	3
7)	Graduates become a role model for colleagues and society through Professional identity.	5
8)	Graduates are competent enough to understand the anatomy, physiological functions and behavior of healthy individuals and/or the patients; it is empowering to understand the relationship between the individual's health and the physical and social environment.	5
9)	As an individual, he acts in accordance with laws, regulations, legislation and professional codes of ethics regarding his duties, rights and responsibilities.	5
10)	Cooperate with persons from related disciplines and act in accordance with social, scientific, cultural and ethical values at the stages of data collection, interpretation, application and announcement of results related to the health field.	3

Learning Activity and Teaching Methods

Brainstorming/ Six tihnking hats
Individual study and homework
Lesson
Reading
Q&A / Discussion

Assessment & Grading Methods and Criteria

Written Exam (Open-ended questions, multiple choice, true-false, matching, fill in the blanks, sequencing)
Presentation
Bilgisayar Destekli Sunum

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Project	1	% 40
Midterms	1	% 0
Final	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

Workload and ECTS Credit Grading

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	2	28
Study Hours Out of Class	4	8	32
Midterms	1	14	14
Final	1	56	56
Total Workload			130